Ketoprofen belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs) and is prescribed to relieve pain and swelling commonly associated with arthritis and sports-related injuries. A pulled muscle or a stiff joint is something that can always be treated with ketoprofen. Available in the form of creams and gels, its application can work wonders to alleviate musculoskeletal pain. Spondylitis patients may also find relief by regularly applying this cream. Although the medicine is sold in capsule form, using its topical version is always better for reducing inflammatory pain. This is because, it is applied topically on the affected area. Hence, side effects, if any, usually remain localized and do not involve the whole body. Ketoprofen Ingredients The primary ingredient in this pain-killing topical formulation is ketoprofen, a proven analgesic and anti-inflammatory agent. Usually, the cream contains 10-20% concentration of ketoprofen. The one available in the gel form has 2.5% ketoprofen by weight. Side Effects Photosensitivity Although an effective painkiller, its regular application can make the affected area sensitive to sunlight. So the application site when exposed to sunlight may trigger a burning and stinging sensation. Upon exposure, the affected area may become excessively red and may even lead to sunburn. In such circumstances, during treatment, wearing protective clothing and avoiding sun exposure for prolonged periods, is the best way to deal with sun sensitive skin. Exposure to sunbeds is also a strict no-no until the treatment is over. Itchy Skin Using the ketoprofen cream and gel can also cause skin irritation. The application site may become itchy and dry. Apart from the annoying itchy sensation that causes incessant desire to scratch, skin rash may occur on the application area. Allergic Reaction Those who are allergic to NSAIDs, such as ibuprofen and aspirin, should avoid using this cream as its active ingredient ketoprofen is also an NSAID. The allergic reaction can lead to formation of blisters, and moreover, the person may experience respiratory problems that typically cause stuffy or runny nose. A severe allergic reaction such as facial swelling is rare but requires immediate attention. Excess application of ketoprofen cream is not recommended as it can increase the intensity of some side effects. When applied in moderately, the cream penetrates and reaches the inflamed tissue that is causing pain. However, when applied excessively, it not only penetrates the deeper layers of the skin but also makes it way into the bloodstream, which is a cause for great concern. So, make sure you use the cream as directed by your health care provider. Also, after applying the cream, one should not wrap a bandage around the site of application as the skin may absorb more of the topical medication, which may penetrate the deeper layers and increase the risk of medication being absorbed into the bloodstream. Ketoprofen Cream During Pregnancy Clinical studies are yet to verify the safety of the drug in pregnant women. It has been classified as a pregnancy C drug, meaning animal studies demonstrate the drug can be detrimental to the fetus. Keeping this in mind, ketoprofen in any form is usually not prescribed during pregnancy. Disclaimer: The information provided in this article is solely for educating the reader. It is not intended to be a substitute for the advice of a medical expert.